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Diet-Associated Gut Microbiome Signatures in Pediatric Phenylketonuria: A Shotgun Metagenomic Study from Ecuador

2026-03-16

Abstract excerpt

<title>Abstract</title> <p> Background Phenylketonuria (PKU) requires lifelong phenylalanine (Phe) restriction to prevent neurotoxicity. Dietary management may remodel the gut microbiome, with potential clinical implications. We characterized taxonomic and functional features of the gut microbiome in pediatric PKU patients managed with Phe-restricted versus non-restricted diets in Ecuador. Methods We performed...

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Literature Corpus work
f1626a45-c6aa-5fcc-888b-5c9cb71d8a74
DOI
10.21203/rs.3.rs-9010202/v1
Open publication

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Diet-Associated Gut Microbiome Signatures in Pediatric Phenylketonuria: A Shotgun Metagenomic Study from EcuadorDOI 10.21203/rs.3.rs-9010202/v1
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