Gut Microbiota Dysbiosis and Short-chain Fatty Acid alterations in Pediatric New-Onset Type 1 diabetes with Ketoacidosis

Abstract excerpt

<h4>Objective</h4> Diabetic ketoacidosis (DKA) stands as the most common acute hyperglycaemic complication with a relatively high mortality rate among children diagnosed with type 1 diabetes (T1D). Previous studies have shed light on gut dysbiosis in newly-onset T1D children, but research targeting the gut microbiota and microbial metabolites in patients with DKA remains scarce. <h4>Methods</h4> Shotgun metageno...

Topics

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• Clostridium difficile and Clostridium perfringens research
• Diabetes and associated disorders
• Diabetes Management and Research
• Diet and metabolism studies
• Diet, Metabolism, and Disease
• Gut microbiota and health
• Nutritional Studies and Diet
• Oral microbiology and periodontitis research

Identifiers and source

Literature Corpus work

d105ae51-8506-5530-bdb8-fe6a017ba973

DOI

10.1101/2025.04.22.650027