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Characterization of gut microbiomes in rural Honduras reveals uncharacterized species and associations with human genetic variation.

Cell reports - 27 Jan 2026

Beghini Francesco, Brito Ilana L, Gerstein Mark, Christakis Nicholas A

Abstract excerpt

The gut microbiome is integral to human health, yet research data to date have emphasized industrialized populations. Here, we performed large-scale shotgun metagenomic sequencing on 1,893 individuals from rural Honduras, providing the most comprehensive microbiome dataset from Central America. We identify a distinct microbial composition enriched in Prevotella species. Longitudinal analysis in 301 individuals...

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PMID: 41420859
DOI: 10.1016/j.celrep.2025.116724

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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