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A comprehensive computational investigation into the conserved virulent proteins of <i>Shigella</i> sp unveils potential siRNA candidates as a new therapeutic strategy against shigellosis

2021-03-10

Abstract excerpt

Shigella sp account for the second-leading cause of deaths due to diarrheal diseases among children of less than 5 years of age. Emergence of multi-drug resistant Shigella isolates and the lack of availability of Shigella vaccines have made the efforts in the development of new therapeutic strategies against shigellosis very pertinent. In our study we have analyzed a total of 241 conserved sequences from a 15 di...

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Literature Corpus work
f14e64ca-e2a7-5aaf-9f76-451e311a4f71
DOI
10.1101/2021.03.09.434519
Open publication

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A comprehensive computational investigation into the conserved virulent proteins of <i>Shigella</i> sp unveils potential siRNA candidates as a new therapeutic strategy against shigellosisDOI 10.1101/2021.03.09.434519
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