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Article

A multi-component screen for feeding behaviour and nutritional status in <i>Drosophila</i> to interrogate mammalian appetite-related genes

2020-05-04

Abstract excerpt

More than 300 genetic variants have been robustly associated with measures of human adiposity. Highly penetrant mutations causing human obesity do so largely by disrupting satiety pathways in the brain and increasing food intake. Most of the common obesity-predisposing variants are in, or near, genes that are expressed highly in the brain, but little is known about their function. Exploring the biology of these ge...

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Literature Corpus work
f10da988-f3a1-51e1-9919-ebae25e5fbd0
DOI
10.1101/2020.05.04.076489
Open publication

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A multi-component screen for feeding behaviour and nutritional status in <i>Drosophila</i> to interrogate mammalian appetite-related genesDOI 10.1101/2020.05.04.076489
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