Article
An ex vivo tissue model of cartilage degradation suggests that cartilage state can be determined from secreted key protein patterns
2019-02-05
Abstract excerpt
The pathophysiology of osteoarthritis (OA) involves dysregulation of anabolic and catabolic processes associated with a broad panel of cytokines and other secreted proteins and ultimately lead to cartilage degradation. An increased understanding about the interactions of these proteins by means of systematic in vitro analyses may give new ideas regarding pharmaceutical candidates for treatment of OA and related ca...
Topics
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- Blood Coagulation and Thrombosis Mechanisms
- Cell Adhesion Molecules Research
- Chemokine receptors and signaling
- Connective tissue disorders research
- Osteoarthritis Treatment and Mechanisms
- Protease and Inhibitor Mechanisms
- Rheumatoid Arthritis Research and Therapies
- Viral Infectious Diseases and Gene Expression in Insects
Identifiers and source
- Literature Corpus work
- f0f3a25f-dec9-5d60-a111-d43d89fcd545
- DOI
- 10.1101/541375
