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Development of a <i>Xenopus</i> -based assay for high-throughput evaluation of mucociliary flow

2022-07-13

Abstract excerpt

Motile cilia are organelles lining the surfaces of major organs of the human body and generate directional fluid flow. Ciliary dysfunction has been linked to an emerging class of multisystem disorders, collectively known as motile ciliopathies. Drug screening for ciliopathies is challenging due to the unavailability of high-throughput assays that can evaluate ciliary flow generation. Here, we describe the developm...

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Literature Corpus work
f0f0eea9-84f2-5393-9148-81c272070804
DOI
10.1101/2022.07.12.499724
Open publication

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