Article

Spatial confinement of gene drives: Assessing risk of failure using global sensitivity analysis

2026-02-19

Abstract excerpt

Gene drives allow pest populations to be genetically modified to reduce their harm on agriculture and human health. The genetic modification, or payload, spreads within a target population at rates exceeding normal Mendelian inheritance. While gene drives have demonstrated immense potential in laboratory populations, they present unique challenges. Foremost among these challenges is spatial confinement, or ensurin...

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Literature Corpus work: f073be30-79cc-537b-90b9-cc82e1a13ad6
DOI: 10.64898/2026.02.18.706608

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