Article

Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome

2019-08-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Obesity and its associated diseases are major health problems characterized by extensive metabolic disturbances. Understanding the causal connections between these phenotypes and variation in metabolite levels can uncover relevant biology and inform novel intervention strategies. Recent studies have combined metabolite profiling with genetic instrumental variable (IV) analys...

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Literature Corpus work: f046d385-ad2c-5e18-a676-d58eb56c70e6
DOI: 10.1101/734707

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