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MiR-30a-5p alters epidermal terminal differentiation during aging by regulating BNIP3L/NIX-dependent mitophagy

2021-10-25

Abstract excerpt

Chronological aging is characterized by an alteration of the genes regulatory network. In human skin, epidermal keratinocytes fail to differentiate properly with aging, leading to the weakening of the epidermal function. MiR-30a is particularly overexpressed with epidermal aging, but the downstream molecular mechanisms are still uncovered. The aim of this study was to decipher the effects of miR-30a overexpression...

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Literature Corpus work
f03bedc5-aaa1-5a1f-b6fb-a422515b5ebf
DOI
10.1101/2021.10.25.465713
Open publication

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