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Chronological aging impacts abundance, function and microRNA content of extracellular vesicles produced by human epidermal keratinocytes

27 Nov 2023

Abstract excerpt

The disturbance of intercellular communication is one of the hallmarks of aging. The goal of this study is to clarify the impact of chronological aging on extracellular vesicles (EVs), a key mode of communication in mammalian tissues. We focused on epidermal keratinocytes, the main cells of the outer protective layer of the skin which is strongly impaired in the skin of elderly. EVs were purified from conditioned...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38015712
DOI: 10.18632/aging.205245

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