Short report of potential Myelinogenesis effects of taper up-off of opium tincture in rodent model of multiple sclerosis

Abstract excerpt

Multiple sclerosis (MS) is one of the most common demyelinating autoimmune diseases that affects the central nervous system and is characterized by major immune-mediated myelin and axonal damage or axonal loss explicable to the absence of myelin sheaths. Here we present the early findings of the gene expression study of meylinogenesis-related genes of MS rat models which were treated with a novel protocol of taper...

Topics

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• Dexamethasone
• Drug Evaluation, Preclinical
• Encephalomyelitis, Autoimmune, Experimental
• Immunologic Factors
• Pain Management and Opioid Use
• Pain Mechanisms and Treatments
• Sulfonamides
• Thiazoles

Identifiers and source

Literature Corpus work

f03047f6-9db6-51c7-ad1c-2fd1574df0a0

DOI

10.21203/rs.3.rs-3853761/v1