Article

Non-aging despite high mutation rate – genomic insights into the evolution of Hydra

2022-07-05

Abstract excerpt

<title>Abstract</title> <p>Hydra is a genus of freshwater polyps with remarkable regeneration abilities and a non-senescent phenotype under laboratory conditions. Thus, this animal is particularly interesting for aging research. Here, we gained insights into Hydra's recent genetic evolution by genome sequencing of single cells and whole individuals. Despite its extreme longevity, Hydra does not show a lower somat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ef8d7e8c-fc3a-5b0e-a21e-61bad8b60b70
DOI: 10.21203/rs.3.rs-1670825/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Non-aging despite high mutation rate – genomic insights into the evolution of HydraDOI 10.21203/rs.3.rs-1670825/v1Read

Non-aging despite high mutation rate – genomic insights into the evolution of <i>Hydra</i>Semantic proximity Read

Hydra has mammal-like mutation rates facilitating fast adaptation despite its nonaging phenotype.Semantic proximity Read

<i>Hydra</i> , a model system for deciphering the mechanisms of aging and resistance to agingSemantic proximity Read

Mutational profile of the regenerative process and <i>de novo</i> genome assembly of the planarian <i>Schmidtea polychroa</i>Semantic proximity Read

Deficient autophagy in epithelial stem cells drives aging in the freshwater cnidarian Hydra.Semantic proximity Read

Mutational profile of the regenerative process and de novo genome assembly of the planarian Schmidtea polychroa.Semantic proximity Read

Senescence-induced cellular reprogramming drives cnidarian whole-body regenerationSemantic proximity Read

Autophagy in Hydra: A response to starvation and stress in early animal evolutionSemantic proximity Read

An ancient split of germline and somatic stem cell lineages in HydraSemantic proximity Read

An updated and spatially validated somatic single-cell atlas of <i>Hydractinia symbiolongicarpus</i>Semantic proximity Read

Advancing human disease research with fish evolutionary mutant models.Semantic proximity Read

<i>GNL3</i> is an evolutionarily-conserved stem cell gene influencing cell proliferation, animal growth, and regeneration in the hydrozoan <i>Hydractinia</i>Semantic proximity Read