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<i>GNL3</i> is an evolutionarily-conserved stem cell gene influencing cell proliferation, animal growth, and regeneration in the hydrozoan <i>Hydractinia</i>

2022-04-24

Abstract excerpt

Nucleostemin ( NS ) is a vertebrate gene preferentially expressed in stem and cancer cells, which acts to regulate cell cycle progression, genome stability, and ribosome biogenesis. NS and its paralogous gene, GNL3-like ( GNL3L ), arose in the vertebrate clade after a duplication event from their orthologous gene, G protein Nucleolar 3 ( GNL3 ). Research on invertebrate GNL3 , however, has been limited. To...

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Literature Corpus work
46e3c203-e96a-5586-8360-84e98ddf5624
DOI
10.1101/2022.04.24.489303
Open publication

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