Article

Magnesium Sulphate in Neonatal Hypoxic-Ischemic Encephalopathy: Bridging the Gap Between Molecular Neuroprotection and Clinical Outcomes

2026-07-21

Abstract excerpt

Neonatal hypoxic-ischemic encephalopathy (HIE) remains one of the leading causes of neonatal mortality and long-term neurodevelopmental disability despite therapeutic hypothermia, which provides only partial neuroprotection. Among adjunctive therapies, magnesium sulphate (MgSO4) has emerged as one of the most biologically plausible neuroprotective agents because of its ability to modulate glutamate-mediated excito...

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Literature Corpus work: eec27536-5e06-5753-ba18-472d1ae87dc0
DOI: 10.20944/preprints202607.1491.v1

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