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Shared Genetic Architecture between Gastric Cancer and Medication-Use Phenotypes in East Asians Reveals Lipid-Metabolic Pathways and Candidate Cellular Contexts

2026-05-27

Abstract excerpt

<title>Abstract</title> <p> Background Gastric cancer (GC) remains a major cause of cancer-related mortality in East Asia, but its shared genetic architecture with clinically relevant complex traits remains incompletely defined. We sought to characterize the genetic overlap between GC and medication-use phenotypes using large-scale East Asian genome-wide association study summary statistics. Methods We analyze...

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Literature Corpus work
ee9507b9-205b-597d-bae2-a607500cb151
DOI
10.21203/rs.3.rs-9551319/v1
Open publication

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Shared Genetic Architecture between Gastric Cancer and Medication-Use Phenotypes in East Asians Reveals Lipid-Metabolic Pathways and Candidate Cellular ContextsDOI 10.21203/rs.3.rs-9551319/v1
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