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Article

Cross-phenotype association analysis of gastric cancer: in-silico functional annotation based on the disease-gene network.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Jul 2023

Lee Sangjun, Yang Han-Kwang, Lee Hyuk-Joon, Park Do Joong, Kong Seong-Ho, Park Sue K

Abstract excerpt

BACKGROUND: A gene or variant has pleiotropic effects, and genetic variant identification across multiple phenotypes can provide a comprehensive understanding of biological pathways shared among different diseases or phenotypes. Discovery of genetic loci associated with multiple diseases can simultaneously support general interventions. Several meta-analyses have shown genetic associations with gastric cancer...

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PMID: 36995485
DOI: 10.1007/s10120-023-01380-7

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