Article

Microtubule-associated protein HAUS8 regulates glioma proliferation, invasion and migration through EMT mediated by RhoA/ ROCK1

2026-08-28

Abstract excerpt

<title>Abstract</title> <p>Background Glioma is a highly invasive brain tumor in which epithelial-to-mesenchymal transition (EMT) drives dissemination. The microtubule-associated protein HAUS8 is markedly over-expressed in high-grade gliomas, yet its role in invasion remains undefined. Methods We evaluated HAUS8 expression and prognosis using bioinformatic analyses of TCGA, GTEx, and CGGA datasets. Functional s...

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Literature Corpus work: ee4d7ef9-6709-50fa-b83e-0efa277375f3
DOI: 10.21203/rs.3.rs-10547384/v1

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