Article

A Phase I, single and continuous administration study of Safety, tolerability and pharmacokinetics of neorudin, a noval recombinant anticoagulant protein, in healthy subjects

2024-01-30

Abstract excerpt

AIMS: The aims of the study were to evaluate the tolerability, safety and pharmacokinetics of single and continuous administration of recombinant neorudin (EPR-hirudin, EH) by intravenous injection in healthy subjects, and to provide a safe dosage range for phase II clinical research. METHODS: A single and continuous administration dose phase I clinical study was conducted. Forty-four subjects were received EH as...

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Literature Corpus work: ee29f139-d659-553f-87db-4435cc782ee8
DOI: 10.22541/au.170664618.84732094/v1

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A Phase I, single and continuous administration study of Safety, tolerability and pharmacokinetics of neorudin, a noval recombinant anticoagulant protein, in healthy subjectsDOI 10.22541/au.170664618.84732094/v1Read

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