Article

X-Linked Cancer-Associated Polypeptide (XCP) from <i>lncRNA1456</i> Cooperates with PHF8 to Regulate Gene Expression and Cellular Pathways in Breast Cancer

2025-03-25

Abstract excerpt

<h4>Summary</h4> Recent studies have demonstrated that a subset of long “noncoding” RNAs (lncRNAs) produce functional polypeptides and proteins. In this study, we discovered a 132 amino acid protein in human breast cancer cells named XCP ( X -linked C ancer-associated P olypeptide), which is encoded by lncRNA1456 (a.k.a. RHOXF1P3 ), a transcript previously thought to be noncoding. lncRNA1456 is a pancreas–...

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Literature Corpus work: ee16d5d6-e626-521f-bbd0-c4eef03cafb0
DOI: 10.1101/2025.03.21.644649

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