Back to search

Article

Genomic investigation of a suspected multi-drug resistant <i>Klebsiella pneumoniae</i> outbreak in a neonatal care unit in sub-Saharan Africa

2020-08-07

Abstract excerpt

<h4>ABSTRACT</h4> A suspected outbreak of multi-drug resistant (MDR) Klebsiella pneumoniae in a Malawian neonatal unit was investigated using whole-genome sequencing. Strain-types, virulence and resistance genes of K. pneumoniae isolated from patients from the hospital over a four-year period were identified. A MDR ST340 clone was implicated as the likely outbreak cause.

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
edd73bc5-ca96-5a2b-a150-3ae128a96df9
DOI
10.1101/2020.08.06.236117
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genomic investigation of a suspected multi-drug resistant <i>Klebsiella pneumoniae</i> outbreak in a neonatal care unit in sub-Saharan AfricaDOI 10.1101/2020.08.06.236117
Molecular characterisation of a <i>Klebsiella pneumoniae</i> neonatal sepsis outbreak in a rural Gambian hospital: a retrospective genomic epidemiology investigationSemantic proximity
Molecular Epidemiology of multidrug-resistant <i>Klebsiella pneumoniae, Enterobacter cloacae,</i> and <i>Escherichia coli</i> outbreak among neonates in Tembisa Hospital, South AfricaSemantic proximity
High ward-level and within-sample diversity of <i>Klebsiella pneumoniae</i> on a Malawian neonatal unit revealed by single colony whole genome sequencing and post-enrichment metagenomicsSemantic proximity
Genomic characterization of<i>Klebsiella pneumoniae</i>causing invasive disease in South African infants: observational studies between 2018 to 2023Semantic proximity
Antimicrobial resistance and virulence characteristics of <i>Klebsiella pneumoniae</i> isolates in KenyaSemantic proximity
Extended-Spectrum Beta-Lactamase <i>Klebsiella pneumoniae</i> on a Malawian neonatal unit is amplified by neonates and transmitted by maternal hands, cots and ward surfacesSemantic proximity
Longitudinal analysis within one hospital in sub-Saharan Africa over 20 years reveals repeated replacements of dominant clones of<i>Klebsiella pneumoniae</i>and stresses the importance to include temporal patterns for vaccine design considerationsSemantic proximity
Genomic characterization of multidrug-resistant extended spectrum β-lactamase-producing <i>Klebsiella pneumoniae</i> from clinical samples of a tertiary hospital in South Kivu Province, eastern Democratic Republic of CongoSemantic proximity
Genomic characterization of multidrug-resistant extended spectrum β-lactamase-producing<i>Klebsiella pneumoniae</i>from clinical samples of a tertiary hospital in South Kivu Province, eastern Democratic Republic of CongoSemantic proximity
Genomic comparison of highly related pairs of <i>E. coli</i> and <i>K. pneumoniae</i> isolated from faeces and blood of the same neonatal patients hospitalized with fever in Dar es Salaam, TanzaniaSemantic proximity
Low birthweight neonates and those with long hospital stays are most at risk of antimicrobial-resistant <i>Klebsiella pneumoniae</i> infection in Malawi: implications for antibiotic prescribingSemantic proximity
Genomic epidemiology of <i>Klebsiella pneumoniae</i> neonatal and infant sepsis in Kenyan hospitalsSemantic proximity
Select a neighboring publication to make it the new centre.