Article

P-15 promotes chondrocyte proliferation in osteoarthritis by regulating SFPQ to target the Akt-RUNX2 axis

2023-01-04

Abstract excerpt

<h4>Background: </h4> The disruption of chondrocyte proliferation and differentiation is a critical event during the process of joint injury in osteoarthritis (OA). P-15 peptides could bind to integrin receptors on various precursor cells, promote cell adhesion, release growth factors, and promote the differentiation of osteoblast precursor cells. However, the role it plays in OA, particularly in chondrocyte proli...

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Literature Corpus work: ec99a479-e5bb-5da7-ada5-3a821adb16e4
DOI: 10.21203/rs.3.rs-2426762/v1

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