Article

miR-20b-5p Functions as Tumor Suppressor microRNA by targeting CyclinD1 in Colon Cancer

2020-04-29

Abstract excerpt

<h4>Background: </h4> MicroRNA functions as an oncogenic regulator or tumor suppressor in various human tumors. Bioinformatics analysis revealed that miRNA-20b is related to the tumorigenesis, however, the function of miRNA-20b in colon cancer is still not clear. Methods Apoptosis, cell cycle, expression of CCND1/CDK/FOXM1 axis in HCT116 cells were examined by flow cytometry, western blot, and Immunohistochemistr...

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Literature Corpus work: eb92d633-880e-59bb-8409-9089c69eef3e
DOI: 10.21203/rs.3.rs-24982/v1

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