Article

De Novo Variants Predominate in Autism Spectrum Disorder

2025-07-23

Abstract excerpt

Autism spectrum disorder (ASD) is a common condition with substantial personal and financial burdens of lifelong implication. Multiple twin studies have confirmed a genetic or inherited component at ~80%, higher than any other common condition. However, ASD’s rapidly‐accelerating prevalence, now at 1 in 31 in the USA, appears to defy a predominantly genetic basis and implements our rapidly‐changing environment. A...

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Literature Corpus work: eb7743eb-deec-531d-9bd4-7f4fb6285272
DOI: 10.20944/preprints202507.1979.v1

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