Article

The MuSK-BMP pathway regulates synaptic Nav1.4 localization and muscle excitability

2023-10-29

Abstract excerpt

The neuromuscular junction (NMJ) is the linchpin of nerve-evoked muscle contraction. Broadly considered, the function of the NMJ is to transduce a nerve action potential into a muscle fiber action potential (MFAP). Efficient information transfer requires both cholinergic signaling, responsible for the generation of endplate potentials (EPPs), and excitation, the activation of postsynaptic voltage-gated sodium chan...

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Literature Corpus work: eb497fc0-66d3-5abd-80a7-619e3e6cfdd3
DOI: 10.1101/2023.10.24.563837

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