Article

Seroprevalence and cross-reactivity of neutralizing antibodies to six types of adenoviruses

2024-12-26

Abstract excerpt

<h4>Background</h4> The use of adenoviral vector vaccines is an effective way to induce an antiviral immune response. Most vaccines used worldwide are based on human adenovirus type 5 (Ad5). Pre-existing natural immunity to Ad5 is a limitation to the frequent use of Ad5-based vectors in gene therapy and vaccination. In the present study, we assessed the seroprevalence and cross-reactivity of neutralizing antibodi...

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Literature Corpus work: eb3f5fa1-3f04-5e75-8903-d92cd030362f
DOI: 10.1101/2024.12.26.630365

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