Article

Pathway centered analysis to guide clinical decision-making in precision medicine

2021-04-30

Abstract excerpt

Changes in the human proteome caused by disease before, during and after medical care is phenotype-dependent, so the proteome of each individual at any time point is a snapshot of the body’s response to disease and to disease treatment. Here, we introduce a new concept named differential Personal Pathway index (dPPi). This tool extracts and summates comprehensive disease-specific information contained within an in...

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Literature Corpus work: eb301231-3839-5728-a8a1-90399533b825
DOI: 10.1101/2021.04.30.442131

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