Landscaping of Urine Proteome: Unlocking Diagnostic Potential and Overcoming Unique Challenges

Abstract excerpt

This study explores the application of deep proteomic profiling to extract disease-specific features from urine. Early detection of cancer and other chronic disorders is crucial for better outcomes, but traditional diagnostics as well as emerging genomic-based diagnostics are expensive and invasive. Our research reveals that a select group of urinary proteins can accurately detect early-stage diseases with high se...

Topics

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• Advanced Proteomics Techniques and Applications
• Bioinformatics and Genomic Networks
• Bladder and Urothelial Cancer Treatments
• Clusterin in disease pathology
• Metabolomics and Mass Spectrometry Studies
• Renal and Vascular Pathologies

Identifiers and source

Literature Corpus work

42a4afd9-bd8d-550f-a581-209a8239a006

DOI

10.1101/2023.10.27.23297705