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Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant and epigenetic mechanisms

2021-08-23

Abstract excerpt

<title>Abstract</title> <p>Sulforaphane has been investigated in human pathologies and preclinical models of airway diseases. To provide further mechanistic insights, we explored L-sulforaphane (LSF) in the ovalbumin (OVA)-induced chronic allergic airways murine model, with key hallmarks of asthma. Histological analysis indicated that LSF prevented or reversed OVA-induced epithelial thickening, collagen depositio...

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Literature Corpus work
eb1cfa01-eb0a-589f-af38-38ec33af0810
DOI
10.21203/rs.3.rs-787983/v1
Open publication

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Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant and epigenetic mechanismsDOI 10.21203/rs.3.rs-787983/v1
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