Article

Novel porcine model reveals two distinct LGR5 cell types during lung development and homeostasis

2022-12-11

Abstract excerpt

<h4>ABSTRACT</h4> Cells expressing LGR5 play a pivotal role in homeostasis, repair, and regeneration in multiple organs including skin and gastrointestinal tract, yet little is known about their role in the lung. Findings from mice, a widely used animal model, suggest that lung LGR5 expression differs from that of humans. In this work, using a new transgenic pig model, we identify two main populations of LGR5 +...

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Literature Corpus work: eaf2fce3-a988-59f0-9b5b-0bfa377291c9
DOI: 10.1101/2022.12.09.516617

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