Article

PLAC8 promotes adriamycin resistance via blocking autophagy in breast cancer

2020-04-29

Abstract excerpt

<h4>Background: </h4> Adriamycin (ADM) is currently one of the most effective chemotherapeutic agents in breast cancer treatment. However, growing resistance to ADM can lead to treatment failure and poor outcome. The underlying molecular mechanisms in ADM resistance in breast cancer remains unclear. PLAC8 is reported as a novel highly-conserved protein and functions as an oncogene or tumor suppressor in various tu...

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Literature Corpus work: eaae8f88-3fed-5fe1-8a4e-d7b4b8c5a95a
DOI: 10.21203/rs.3.rs-23618/v1

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