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Article

A comprehensive landscape analysis of autophagy in cancer development and drug resistance

26 Aug 2024

Abstract excerpt

Background Autophagy plays important roles in cancer progression and therapeutic resistance, and the autophagy underlying the tumor pathogenesis and further mechanisms of chemoresistance emergence remains unknown. Methods In this study, via the single-sample gene set enrichment analysis (ssGSEA) method, an autophagy 45-gene list was identified to evaluate samples’ autophagy activity, verified through six GEO...

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PMID: 39253092
DOI: 10.3389/fimmu.2024.1412781

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