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Chemical transformation of xenobiotics by the human gut microbiota

23 Jun 2017

Abstract excerpt

The human gut microbiota makes key contributions to the metabolism of ingested compounds (xenobiotics), transforming hundreds of dietary components, industrial chemicals, and pharmaceuticals into metabolites with altered activities, toxicities, and lifetimes within the body. The chemistry of gut microbial xenobiotic metabolism is often distinct from that of host enzymes. Despite their important consequences for...

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PMID: 28642381
DOI: 10.1126/science.aag2770

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