Article

CDK inhibitors are a promising treatment for malignant melanoma with CIC mutation

2023-09-28

Abstract excerpt

<h4>Background: </h4> Capicua (CIC) is a highly conserved high mobility group protein repressor that is mainly involved in mammalian development and homeostasis. Recent findings have shown that CIC mutation can lead to tumor progression and metastasis in various cancers, while the effect of CIC mutation on melanoma has not been reported. This study investigated the clinical and biological significance of CIC in me...

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Literature Corpus work: e9f1580e-2f5b-58cc-9c8b-09950255281b
DOI: 10.21203/rs.3.rs-3377404/v1

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