Article

CD147 promotes cisplatin resistance in ovarian cancer by inhibiting FOXM1 degradation via PI3k/Akt-GSK3β pathway

2023-01-24

Abstract excerpt

CD147 is a transmembrane glycoprotein that is highly expressed in a number of human cancers, including ovarian cancer. The antibody drug Licartin®, which targets CD147, has been approved by the Chinese Food and Drug Administration (FDA) and entered clinical treatment. Some studies have shown that CD147 plays a role on drug resistance, but the molecular mechanism remains elusive. This study sought to investigate th...

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Literature Corpus work: 44e4fb7b-4672-57d2-9099-f38ebb534352
DOI: 10.21203/rs.3.rs-2474599/v1

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