Article

Sparse canonical correlation to identify breast cancer related genes regulated by copy number aberrations

2021-09-02

Abstract excerpt

<h4>Background</h4> Copy number aberrations (CNAs) in cancer affect disease outcomes by regulating molecular phenotypes, such as gene expressions, that drive important biological processes. To gain comprehensive insights into molecular biomarkers for cancer, it is critical to identify key groups of CNAs, the associated gene networks, regulatory modules, and their downstream effect on outcomes. <h4>Methods</h4> In...

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Literature Corpus work: e9cdd28b-ddf5-5cc9-89b0-a9402f9a3716
DOI: 10.1101/2021.08.29.21262811

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