Back to search

Article

An 8-lncRNA signature predicts survival of triple-negative breast cancer patients without germline BRCA1/2 mutation

2020-08-28

Abstract excerpt

<title>Abstract</title> <p>Background Triple-negative breast cancer (TNBC) is a particular breast cancer subtype with poor prognosis due to its aggressive biological behavior and strong heterogeneity. TNBC with germline BRCA1/2 mutation (gBRCAm) have higher sensitivity to DNA damaging agents including platinum-based chemotherapy and PARP inhibitors. But the treatment of TNBC without gBRCAm remains challenging. T...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e9874187-6e3a-5f49-823a-6747aa4fb7c9
DOI
10.21203/rs.3.rs-66893/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
An 8-lncRNA signature predicts survival of triple-negative breast cancer patients without germline BRCA1/2 mutationDOI 10.21203/rs.3.rs-66893/v1
An 8-lncRNA Signature Predicts Survival of Triple-Negative Breast Cancer Patients Without Germline BRCA1/2 MutationSemantic proximity
An 8-lncRNA signature predicts the survival of triple-negative breast cancer patients without germline BRCA1/2 mutationSemantic proximity
The Early-Stage Triple-Negative Breast Cancer Landscape Derives a Novel Prognostic Signature and Therapeutic TargetSemantic proximity
Molecular Classification of Breast Cancer Utilizing Long Non-Coding RNA (lncRNA) Transcriptomes Identifies Novel Diagnostic lncRNA Panel for Triple-Negative Breast CancerSemantic proximity
Malignant cell related gene signature for patients with triple-negative breast cancer based on integrated analysis of single cell and bulk RNA sequencingSemantic proximity
Development of a Prognostic Model Based on Identification of EMT-related LncRNAs in Triple Negative Breast CancerSemantic proximity
Transcriptome Analysis Derives a Novel Prognostic 7-mRNA Signature in Early-Stage Triple-Negative Breast CancerSemantic proximity
Decoding molecular signatures and identifying therapeutic targets in triple-negative breast cancer subtypes using omics and network analysis.Semantic proximity
A three-long noncoding RNA signature as a diagnostic biomarker for differentiating between triple-negative and non-triple-negative breast cancersSemantic proximity
Identification and validation of molecular subtypes and a 9-gene risk model for breast cancer.Semantic proximity
m6A-related lncRNAs are potential biomarkers for predicting prognoses in patients with breast cancerSemantic proximity
New Biomarkers and Treatment Advances in Triple-Negative Breast CancerSemantic proximity
Select a neighboring publication to make it the new centre.