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An 8-lncRNA Signature Predicts Survival of Triple-Negative Breast Cancer Patients Without Germline BRCA1/2 Mutation

2020-08-20

Abstract excerpt

<h4>Background: </h4> Triple-negative breast cancer (TNBC) is a particular breast cancer subtype with poor prognosis due to its aggressive biological behavior and strong heterogeneity. TNBC with germline BRCA1/2 mutation (gBRCAm) have higher sensitivity to DNA damaging agents including platinum-based chemotherapy and PARP inhibitors. But the treatment of TNBC without gBRCAm remains challenging. This study aimed to...

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Literature Corpus work
0b398e4d-6ea9-52da-b735-93e2857da168
DOI
10.21203/rs.3.rs-60544/v1
Open publication

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An 8-lncRNA Signature Predicts Survival of Triple-Negative Breast Cancer Patients Without Germline BRCA1/2 MutationDOI 10.21203/rs.3.rs-60544/v1
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