Article
RNA sequencing of the i <i>n vivo</i> human herpesvirus 6B transcriptome to identify targets for clinical assays distinguishing between latent and active infections
2018-08-22
Abstract excerpt
<h4>ABSTRACT</h4> Human herpesvirus 6B (HHV-6B) DNA is frequently detected in human samples, especially after hematopoietic cell transplantation (HCT). Diagnostic assays distinguishing HHV-6B reactivation from latency are limited, and this has contributed to confusion in research and made the design of clinical approaches to diagnose and treat HHV-6-associated diseases challenging. We used RNA sequencing to chara...
Topics
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- Cancer-related molecular mechanisms research
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Parvovirus B19 Infection Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Polyomavirus and related diseases
- Transplantation: Methods and Outcomes
- Viral-associated cancers and disorders
Identifiers and source
- Literature Corpus work
- e984e7b5-a10f-5de5-9748-7be2f393ee6b
- DOI
- 10.1101/397679
