Article
Human herpesvirus 6B (HHV-6B) detection and genome-wide host expression profiles implicate HHV-6B as a pulmonary pathogen after hematopoietic cell transplantation
2023-09-28
Abstract excerpt
<title>Abstract</title> <p>Limited understanding of the immunopathogenesis of human herpesvirus 6B (HHV-6B) has prevented its acceptance as a pulmonary pathogen after hematopoietic cell transplantation (HCT). We conducted a prospective multicenter study of patients undergoing bronchoalveolar lavage (BAL) for pneumonia after allogeneic HCT. We tested blood and BAL fluid (BALF) for HHV-6B DNA and mRNA transcripts a...
Topics
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- CAR-T cell therapy research
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Polyomavirus and related diseases
- Transplantation: Methods and Outcomes
- Viral-associated cancers and disorders
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- d94edb5b-8e09-5d0e-a3cf-49174a30d5ad
- DOI
- 10.21203/rs.3.rs-3361983/v1
