Article

Breakthrough in Functional Muscle Regeneration: Biomimetic Collagen Scaffold Restores Abdominal Wall Defects in a VML-rabbit Model

2025-06-08

Abstract excerpt

Functional regeneration of volumetric muscle loss (VML) remains a significant challenge in the field of regenerative medicine. We have developed a novel biomimetic scaffold (0.4 mm thick hernia patch) derived from soluble collagen. This biomimetic scaffold exhibits exceptional strength, low immunogenicity, and structurally mimics the natural muscle fiber arrangement. The scaffold is utilized to repair a VML rabbit...

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Literature Corpus work: e97b1e95-c405-5bb0-b08b-2513dc2151ae
DOI: 10.1101/2025.06.07.657281

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