Article

Dynamics and recognition of homeodomain containing protein-DNA complex of IRX4

2022-01-20

Abstract excerpt

Iroquois Homeobox 4 (IRX4) belongs to a family of homeobox TFs having roles in embryogenesis, cell specification and organ development. Recently, Large scale Genome-Wide Association studies and epigenetic studies have highlighted the role of IRX4 and its associated variants in prostate cancer. No studies have investigated and characterized the structural aspect of the IRX4 homeodomain and its potential to bind to...

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Literature Corpus work: e9762513-e25e-5d05-86dd-c06ddd506119
DOI: 10.22541/au.164271893.36410349/v1

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