Article

Coronavirus Disease 2019 (COVID-19) Binding Mechanism with Human ACE2: A Computational Approach

2020-04-19

Abstract excerpt

The outbreak across the globe due to coronavirus disease 2019 (COVID-19) has spread abruptly by infected humans worldwide. The continuous efforts by scientists is on way to understand how pandemic of COVID-19 resembles and differs from serve acute respiratory syndrome coronavirus (SARS-CoV) at transcriptomic and genomic level. The SARS-CoV and COVID-19 exploits the angiotensin converting enzyme 2 (ACE2) receptor t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e8d02eba-670f-5f97-b25f-00cfb42e76d2
DOI: 10.20944/preprints202004.0332.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Coronavirus Disease 2019 (COVID-19) Binding Mechanism with Human ACE2: A Computational ApproachDOI 10.20944/preprints202004.0332.v1Read

The Binding Mechanism of Coronavirus Disease 2019 with Human Angiotensin Converting Enzyme 2Semantic proximity Read

Angiotensin Converting Enzyme 2 in Coronavirus Disease (COVID-19): Evidence from Bioinformatics AnalysisSemantic proximity Read

Experimental and clinical data analysis for identification of COVID-19 resistant ACE2 mutations.Semantic proximity Read

In Silico Prediction of New Mutations That Can Improve the Binding Abilities Between 2019-nCoV Coronavirus and Human ACE2.Semantic proximity Read

Computational optimization of the SARS-CoV-2 receptor-binding-motif affinity for human ACE2Semantic proximity Read

Computational simulations reveal the binding dynamics between human ACE2 and the receptor binding domain of SARS-CoV-2 spike proteinSemantic proximity Read

Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodiesSemantic proximity Read

Does SARS-CoV-2 Bind to Human ACE2 More Strongly Than Does SARS-CoV?Semantic proximity Read

Docking of Velpatasvir to the SARS-CoV-2 Viral Spike Protein-Human ACE2 Complex: repurposing for COVID-19Semantic proximity Read

Interaction of SARS-CoV-2 with host cells and antibodies: experiment and simulationSemantic proximity Read

Influenza Viral Infection is a High-Risk Factor for Developing Coronavirus Disease 2019 (COVID-19)Semantic proximity Read

Critical Sequence Hot-spots for Binding of nCOV-2019 to ACE2 as Evaluated by Molecular SimulationsSemantic proximity Read