High throughput SARS-CoV-2 variant analysis using molecular barcodes coupled with Next Generation Sequencing

Abstract excerpt

The identification of SARS-CoV-2 variants across the globe and their implications on the outspread of the pandemic, infection potential and resistance to vaccination, requires modification of the current diagnostic methods to map out viral mutations rapidly and reliably. Here, we demonstrate that integrating DNA barcoding technology, sample pooling and Next Generation Sequencing (NGS) provide an applicable solutio...

Topics

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• COVID-19
• Genomics
• High-Throughput Nucleotide Sequencing
• Mutation
• RNA
• SARS-CoV-2
• Spike Glycoprotein, Coronavirus
• Whole Genome Sequencing

Identifiers and source

Literature Corpus work

e8527847-a45a-5dfc-b76c-0b5c18752b45

DOI

10.1101/2021.05.27.21257726