Article
Genotyping SARS-CoV-2 Variants Using Ratiometric Nucleic Acid Barcode Panels.
Analytical chemistry - 11 Apr 2023
Kozlowski Hannah N, Malekjahani Ayden, Li Vanessa Y C, Lekuti Ayokunle A, Perusini Stephen, Bell Natalie G, Voisin Veronique, Pouyabahar Delaram, Pai Shraddha, Bader Gary D, Mubareka Samira, Gubbay Jonathan B, Chan Warren C W
Abstract excerpt
Designing diagnostic assays to genotype rapidly mutating viruses remains a challenge despite the overall improvements in nucleic acid detection technologies. RT-PCR and next-generation sequencing are unsuitable for genotyping during outbreaks or in point-of-care detection due to their infrastructure requirements and longer turnaround times. We developed a quantum dot barcode multiplexing system to genotype...
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