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Upregulation of DNA repair genes and cell extrusion underpin the remarkable radiation resistance of <i>Trichoplax adhaerens</i>

2020-12-24

Abstract excerpt

Trichoplax adhaerens is the simplest multicellular animal with tissue differentiation and somatic cell turnover. Like all other multicellular organisms, it should be vulnerable to cancer, yet there have been no reports of cancer in T. adhaerens , or any other placozoan. We investigated the cancer resistance of T. adhaerens , discovering that they are able to tolerate high levels of radiation damage (218.6 Gy). T...

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Literature Corpus work
e7c5cf47-39f8-5f81-95bc-fe405af7cc9d
DOI
10.1101/2020.12.24.424349
Open publication

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