Article

Comparative transcriptomics reveal a novel tardigrade-specific DNA-binding protein induced in response to ionizing radiation

2024-07-09

Abstract excerpt

Tardigrades are microscopic animals renowned for their ability to withstand extreme conditions, including high doses of ionizing radiation (IR). To better understand their radio-resistance, we first characterized induction and repair of DNA double- and single-strand breaks after exposure to IR in the model species Hypsibius exemplaris . Importantly, we found that the rate of single-strand breaks induced was roughl...

Topics

Open a Topic to create a Post that cites this publication.

Spaceflight effects on biology

Identifiers and source

Literature Corpus work: 7a492ca3-87cb-55c3-9578-14b0ac086b11
DOI: 10.7554/elife.92621.3

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comparative transcriptomics reveal a novel tardigrade-specific DNA-binding protein induced in response to ionizing radiationDOI 10.7554/elife.92621.3Read

Comparative transcriptomics reveal a novel tardigrade-specific DNA-binding protein induced in response to ionizing radiationSemantic proximity Read

Comparative transcriptomics reveal a novel tardigrade specific DNA binding protein induced in response to ionizing radiationSemantic proximity Read

Tardigrades dramatically upregulate DNA repair pathway genes in response to ionizing radiationSemantic proximity Read

Radiation Tolerance in Tardigrades: Current Knowledge and Potential Applications in MedicineSemantic proximity Read

Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique proteinSemantic proximity Read

DNA Protection Protein, a Novel Mechanism of Radiation Tolerance: Lessons from TardigradesSemantic proximity Read

Transcriptome Analysis in Tardigrade Species Reveals Specific Molecular Pathways for Stress AdaptationsSemantic proximity Read

Time-series transcriptomic screening of factors contributing to the cross-tolerance to UV radiation and anhydrobiosis in tardigradesSemantic proximity Read

In Silico Analysis of the Association of Damage Suppressor (Dsup) Proteins of Tardigrades with BRCA1 Protein of Homo sapiensSemantic proximity Read

Iron Ladies – How Desiccated Asexual Rotifer Adineta vaga Deal With X-Rays and Heavy Ions?Semantic proximity Read

The biomedical potential of tardigrade proteins: A reviewSemantic proximity Read

The Tardigrade Damage Suppressor Protein Promotes Transcription Factor Activation and Expression of DNA Repair Genes in Human Cells in Response to Hydroxyl Radicals and UV-C ExposureSemantic proximity Read