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Article

Dynamic Regulation of SARS-CoV-2 Binding and Cell Entry Mechanisms in Remodeled Human Ventricular Myocardium

2020-04-22

Abstract excerpt

Objectives: In intact Nonfailing (NF) and failing/remodeled left ventricles (LVs) in patients with nonischemic dilated cardiomyopathies (F/NDC), measure gene expression of elements required for SARS-CoV-2 cell binding and entry, to determine: 1) whether the CoV-2 binding cell membrane receptor ACE2 is up-regulated; 2) if host cell proteases required for CoV-2 cell entry are expressed and/or up-regulated; and 3) wh...

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Identifiers and source

Literature Corpus work
e7b51507-79da-5162-9d7b-f4a0498ac708
DOI
10.2139/ssrn.3595038
Open publication

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Dynamic Regulation of SARS-CoV-2 Binding and Cell Entry Mechanisms in Remodeled Human Ventricular MyocardiumDOI 10.2139/ssrn.3595038
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