Article

An automated image analysis pipeline for wide-field optical redox imaging of patient-derived cancer organoids

2025-10-31

Abstract excerpt

Wide-field optical redox imaging provides a fast and accessible method to monitor metabolic changes in cells and has recently been developed for drug screening in patient-derived cancer organoids (PDCOs). However, manual analysis of wide-field optical redox images is inefficient and laborious for large-scale drug screens. Here, we developed an automated pipeline for PDCO segmentation, single-PDCO tracking, and bac...

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Literature Corpus work: e75f208d-fd79-5aab-b402-1b8d928a2bf8
DOI: 10.1101/2025.10.29.685427

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