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RoAM: computational reconstruction of ancient methylomes and identification of differentially methylated regions

2024-08-08

Abstract excerpt

Identifying evolutionary changes in DNA methylation bears a huge potential for unraveling adaptations that have occurred in modern humans. Over the past decade, computational methods to reconstruct DNA methylation patterns from ancient DNA sequences have been developed, allowing for the exploration of DNA methylation changes during the past hundreds of thousands of years of human evolution. Here, we introduce a ne...

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Literature Corpus work
e7557788-12c5-553f-af31-372803337cc7
DOI
10.1101/2024.08.08.607143
Open publication

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RoAM: computational reconstruction of ancient methylomes and identification of differentially methylated regionsDOI 10.1101/2024.08.08.607143
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